What are the Side Effects of Naltrexone for Addiction?

While naltrexone is an effective tool for reducing alcohol cravings, you may experience some initial side effects as your body adjusts to the medication. Most of these symptoms are considered mild and typically resolve on their own within the first week of consistent use.

The most common side effects of naltrexone include:

  • Nausea: Often the most reported effect, which can frequently be managed by taking the medication with food.
  • Headaches: These are generally temporary and diminish as treatment continues.
  • Dizziness: You may feel lightheaded during the first few days of therapy.
  • Fatigue: Some individuals report feeling more tired than usual when beginning the medication.

At our center in Easton, PA, we take an evidence-based and holistic approach to managing your care. If side effects are a concern, our clinical team can help manage them by adjusting your starting dose—such as beginning at 25 mg before moving to the standard 50 mg dose—and providing attentive monitoring every two to four weeks.

It is also important to note the differences in the side effect profiles between the daily oral tablet and Vivitrol (the monthly injection). While they share the same general side effects, Vivitrol may also cause localized reactions at the injection site, such as pain, swelling, or a small lump.

Information on this site is not a substitute for professional medical advice. Results may vary. Always consult a healthcare professional for diagnosis and treatment recommendations.


Related FAQs