How does Naltrexone Work for Alcohol Use Disorder?

Naltrexone for alcohol use disorder works by blocking the brain’s opioid receptors. In our evidence-based Medication-Assisted Treatment (MAT) program, we utilize this medication to help reduce the intense cravings that often lead to heavy drinking.

When you consume alcohol, your body releases endorphins—natural opioids—that create a rewarding, pleasurable sensation. As an opioid receptor antagonist, naltrexone essentially acts as a shield over these receptors, preventing alcohol from triggering that euphoric response. By disrupting this reward circuitry, the medication makes it easier for you to regain control and focus on the emotional work of therapy.

We offer naltrexone in two forms to best fit your lifestyle:

  • Oral Naltrexone: A daily 50 mg tablet that requires consistent self-administration.
  • Vivitrol: A long-acting, once-monthly injection administered by a healthcare professional, which can simplify treatment adherence by eliminating the need for a daily pill.

At our center in Easton, PA, we believe in treating the whole person. While naltrexone is a powerful tool for managing cravings, it is most effective when integrated with our holistic services, such as Individual Therapy, Group Therapy, and wellness practices like mindfulness.

Information on this site is not a substitute for professional medical advice. Results may vary. Consult a healthcare professional for diagnosis and treatment recommendations.


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